Chemical laboratory

Methanol Di Water Solution

High-Purity Solvent Mixture for Laboratory Applications

  • CAS Mixture
  • Formula CH₄O/H₂O (Mixture, variable composition)
  • Flash Pt Variable, depends on composition. 11 °C (pure Methanol)
  • Density Variable, depends on composition. 0.791 g/cm³ (pure Methanol)
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Physical & Chemical Properties

Property Value Unit
Boiling point Variable, depends on composition. 64.7 °C (pure Methanol) °C
Flash point Variable, depends on composition. 11 °C (pure Methanol) °C
Density Variable, depends on composition. 0.791 g/cm³ (pure Methanol) g/cm³
Solubility Miscible with water -
Ph Approximately 7.0 (neutral) -
Molecular weight Varies g/mol
Melting point Variable, depends on composition. -97.8 °C (pure Methanol) °C
Vapor pressure Variable, depends on composition. 127 mmHg at 20°C (pure Methanol) mmHg
Autoignition temp Variable, depends on composition. 464 °C (pure Methanol) -
Appearance Clear, colorless liquid -
Odor Slight alcohol odor -
Vapor density Variable, depends on composition. 1.11 (air = 1) (pure Methanol) g/cm³

Overview

Methanol Di Water Solution is a versatile solvent mixture combining methanol and deionized water in precise proportions. This clear, colorless liquid mixture maintains the beneficial properties of both components while offering customizable composition ratios for specific analytical and preparative applications. As a miscible solution, it provides excellent solvating power for both polar and moderately polar compounds, making it an essential reagent in modern analytical laboratories and chemical processing facilities.

Key Applications

This high-purity solvent mixture excels in HPLC mobile phase preparation, where precise methanol-water ratios are critical for optimal separation efficiency and peak resolution in liquid chromatography systems. The solution serves as an ideal protein precipitation agent in biochemical analysis, effectively removing proteins from complex biological samples while preserving target analytes for quantitative analysis.

  • LC-MS sample preparation and dilution for mass spectrometry applications
  • Solvent extraction procedures requiring controlled polarity gradients
  • GC sample dilution for gas chromatography analysis
  • Calibration solutions for analytical instrument standardization

Safety & Handling

The flash point varies with composition but approaches 11°C for methanol-rich mixtures, requiring careful handling around ignition sources. Always use in well-ventilated areas or under fume hoods to prevent vapor accumulation. Required personal protective equipment includes chemical-resistant gloves, safety goggles, and laboratory coats. Ground all equipment when transferring to prevent static discharge, and maintain adequate ventilation to keep vapor concentrations below occupational exposure limits.

Storage & Shelf Life

Store in tightly sealed containers away from heat sources, sparks, and oxidizing agents in a cool, dry location below 25°C. Use chemical-resistant containers such as glass or appropriate plastic materials. Keep away from acids, bases, and strong oxidizers that may cause incompatible reactions. Properly stored material maintains stability for extended periods when protected from contamination and evaporation.

Why Alliance Chemical

Alliance Chemical delivers Methanol Di Water Solution with same-day shipping from our Taylor, Texas facility. We offer flexible shipping options including UPS for smaller quantities and LTL/FTL freight for bulk orders. Every shipment includes comprehensive Safety Data Sheets (SDS) and Certificates of Analysis (COA) to ensure product quality and regulatory compliance for your laboratory operations.

Shipping & Availability

Parcel Shipping

UPS Ground supports pints, quarts, and most 1-gallon packages nationwide.

LTL Freight

5-gallon pails, drums, and totes move via LTL carriers such as ABF Freight, SEFL, Saia, and XPO.

Full Truckload

FTL available for palletized bulk orders. Competitive freight rates.

Local Pickup

Will-call pickup available at our Taylor, TX warehouse for Texas customers.

SDS, COA, and TDS available for every product • Most orders ship in 1-2 business days from Taylor, TX

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Select your state for local shipping times, industry applications, and ordering details.

Frequently Asked Questions

What is a methanol/DI water solution and what is it used for?
A methanol/DI water solution is a mixture of methanol and deionized water used as a solvent blend, antifreeze, cleaning agent and laboratory reagent. It is commonly used in industrial cleaning, chromatography mobile phases, analytical sample preparation and process testing where controlled solvent strength and low ionic content are required.
How should I store methanol/DI water solutions and what is the typical shelf life?
Store in a cool, well-ventilated area away from ignition sources in tightly closed, approved containers (glass, HDPE or compatible stainless steel) and avoid direct sunlight. Typical sealed shelf life is 12–24 months, but verify the supplier COA/SDS and store-by date for grade-specific guidance.
What are the main safety hazards and handling precautions for methanol/water mixtures?
Methanol solutions are highly flammable and toxic if ingested or absorbed; handle in a fume hood or well-ventilated area, wear chemical-resistant gloves (e.g., nitrile), splash goggles and protective clothing, and avoid inhalation and skin contact. Keep away from heat, sparks and open flames, have suitable fire extinguishers available, and follow emergency procedures on the SDS.
How do different methanol concentrations change performance and hazards?
Higher methanol concentrations increase solvent strength, volatility and flammability and lower the freezing point, while lower concentrations reduce flammability and increase conductivity. Select concentration based on required solvent power, freezing-point depression and applicable safety or regulatory limits.
What documentation can I get for a methanol/DI water solution?
Suppliers typically provide a Safety Data Sheet (SDS), Certificate of Analysis (COA) and Technical Data Sheet (TDS) showing concentration, impurities and test methods. Request batch-specific COAs and analytical method details (e.g., GC, Karl Fischer) for critical applications.
How is methanol/DI water solution shipped and what packaging options are available?
Shipping is regulated as a flammable liquid and classification/documentation depend on methanol concentration and local carrier rules; carriers will require appropriate hazard paperwork. Common packaging options include small bottles, pails, drums, IBCs and bulk tank deliveries using UN‑approved containers and secondary containment as needed.
Which materials are compatible or incompatible with methanol/water mixtures?
Compatible materials include stainless steel (e.g., 316), glass, PTFE, HDPE and many fluoropolymers, while incompatibilities can include certain aluminum alloys, copper/brass and elastomers (natural rubber, some neoprenes) that may swell or degrade. Always confirm compatibility for seals, gaskets and paints or perform a compatibility test for long-term contact.
What technical specifications should I verify before using or ordering this solution?
Key specs to verify are methanol concentration (wt/vol %), assay/purity, water content/resistivity, density/specific gravity, freezing point and impurity limits (e.g., formaldehyde, other organics). Request the COA and the analytical methods used so the material meets your process or analytical requirements.
What industries and laboratory applications commonly use methanol/DI water solutions?
Common users include chemical and coatings manufacturers, petrochemical and automotive testing labs, electronics cleaning, environmental and analytical laboratories for HPLC mobile phases, sample prep and solvent rinsing. It is selected where adjustable solvent strength with low ionic content is required.
How do I purchase methanol/DI water solution and what availability options exist?
Methanol/DI water solutions are available from chemical suppliers in small bottles, drums, IBCs and bulk tank shipments, and suppliers normally offer standard grades (technical, reagent, HPLC) or custom concentrations. Contact your supplier for pricing, minimum order quantities, lead times, available grades and to obtain SDS/COA prior to purchase.

Documentation & Downloads

Safety Data Sheet
SDS / MSDS
Request COA
Certificate of Analysis
Technical Data Sheet (TDS)
Available for all products

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